Thursday 4 August 2011

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Wednesday 3 August 2011

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Tuesday 2 August 2011

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Curcumin and melanoma

Can a spice help fight cancer?

By Cory Hatch
7/11/05
The Asian spice that gives curried rice its bright yellow color could someday provide researchers with a new way to fight skin cancer. Small doses of curcumin, a spice ground from the turmeric root and a common ingredient in curry, not only stopped the growth of melanoma cells in the lab but also caused the cells to self-destruct, say researchers from the University of Texas's M. D. Anderson Cancer Center in Houston.
The researchers tested curcumin on lab-grown melanoma cells to see if the spice could stop the cells from surviving and reproducing. The more curcumin they added to the melanoma, the more cells died. Unlike normal cells, cancer cells grow uncontrollably and do not self-destruct. Increased doses of curcumin also stopped the melanoma cells from reproducing.
One coauthor of the paper, which will be published in the August 15 issue of the journal Cancer, Bharat Aggarwal, said curcumin is intriguing to researchers because of its low toxicity. While most forms of chemotherapy cause serious adverse reactions in cancer patients, studies have shown that people can tolerate large amounts of curcumin with no ill effects. Curcumin also works as an antioxidant and an anti-inflammatory agent.
"People from countries like India have been taking it for thousands of years," says Aggarwal. "It is well tolerated. Here is a completely nontoxic anti-inflammatory agent."
Doctors diagnose roughly 53,600 people with melanoma each year. The cancerous cells develop as irregularly shaped and colored moles on the surface of the skin. The cancer resists many chemotherapy treatments and can metastasize, spreading to other organs in the body.
Aggarwal and his colleagues believe that curcumin blocks the signals a cancer cell needs to survive. David Fisher, director of the melanoma program at the Dana Farber Cancer Institute, said that looking at how curcumin blocks these signals was one of the more important discoveries in this paper.
But is Indian food really a cure for cancer? While this laboratory evidence is interesting, researchers say, it doesn't prove that curcumin will help fight cancer in humans. "It's way in its infancy," Allan Halpern, chief of dermatology at Memorial Sloan-Kettering Cancer Center, says of the research. "The problem is that, to date, we do not have is clinical data to support the fact that using these agents as a chemo-preventative strategy is effective."
In the meantime, Aggarwal and his colleagues continue to tests curcumin on a wide variety of cancers, including breast cancer. "Curcumin is a perfect alternative [to chemotherapy], but we have to prove that it works," he says.
Find out more: The National Cancer Institute has an extensive web page on melanoma.
Abstract online: www3.interscience.wiley.com
 

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Sunday 31 July 2011

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Saturday 30 July 2011

What is Curcumin?

Curcumin - What is Curcumin?

news-medical.net/health/Curcumin-What-is-Curcumin.aspx

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae).
The other two curcuminoids are desmethoxycurcumin and bis-desmethoxycurcumin. The curcuminoids are polyphenols and are responsible for the yellow color of turmeric. Curcumin can exist in at least two tautomeric forms, keto and enol. The enol form is more energetically stable in the solid phase and in solution.
Turmeric Roots: Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric
Turmeric Roots: Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric
Curcumin can be used for boron quantification in the so-called curcumin method. It reacts with boric acid forming a red colored compound, known as rosocyanine.
Curcumin is brightly yellow colored and may be used as a food coloring. As a food additive, its E number is E100 .

Further Reading


This article is licensed under the Creative Commons Attribution-ShareAlike License. It uses material from the Wikipedia article on "Curcumin" All material adapted used from Wikipedia is available under the terms of the Creative Commons Attribution-ShareAlike License. Wikipedia® itself is a registered trademark of the Wikimedia Foundation, Inc.

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ScienceDaily: Alzheimer's News

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How a Gene Linked to Both Alzheimer's Disease and Type 2 Diabetes Works

July 28, 2011 — Researchers have identified how a gene for a protein that can cause type 2 diabetes, also possibly kills nerve cells in the brain, thereby contributing to Alzheimer's ... > full story

Vitamin D, Curcumin May Help Clear Amyloid Plaques Found In Alzheimer's Disease

Vitamin D, Curcumin May Help Clear Amyloid Plaques Found In Alzheimer's Disease

ScienceDaily (July 16, 2009) — UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer's disease.

Friday 29 July 2011

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Thursday 28 July 2011

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Wednesday 27 July 2011

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Curcumin Turmeric it is used as an antiseptic and an anti-inflammatory agent, As per Indian Ayurveda text turmeric can be taken on a daily basis to improve body immunity.
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Saturday 23 July 2011

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Friday 22 July 2011

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Wednesday 20 July 2011

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Monday 18 July 2011

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Monday 11 July 2011

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Friday 8 July 2011

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Wednesday 6 July 2011

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Saturday 2 July 2011

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Tuesday 28 June 2011

Organic Red Yeast Rice: SimplyPure Red Yeast Rice Supplements

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Uses


Culinary The dried grain can be prepared and eaten in the same manner as white rice—a common practice among Asians. It can also be added to other foods.

Red yeast rice is used to colour a wide variety of food products, including pickled tofu, red rice vinegar, char siu, Peking Duck,
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Red Yeast Rice Lowers Cholesterol: Study Backs Up Centuries of Traditional Use

6/30/2009 - Research just published in the Annals of Internal Medicine concludes a nonprescription, natural supplement -- red yeast rice -- has significant cholesterol-lowering effects. However, one important part of this story is that this isn't really a new discovery at all. Red yeast rice, a bright reddish purple...
Learn more: red yeast rice news and articles http://www.naturalnews.com/red_yeast_rice.html#ixzz1QalW9cIe


Cholesterol

News & Headlines

Red Yeast Rice May Lower Cholesterol, So Why Isn’t Your Doctor Recommending It?

http://news.health.com/2009/06/15/red-yeast-rice-supplements-cholesterol/


By NANCY WALSH, MedPage Today Staff Writer

Oct. 25, 2010
Researchers have found wide variations in the amount of active compounds known as monacolins -- related to prescription drugs called statins -- in different brands of the popular dietary supplement red yeast rice.

Independent testing found that levels of total monacolins in 12 brands of red yeast rice ranged from 0.31 mg to 11.15 mg per capsule, according to Dr. Ram Y. Gordon, of the University of Pennsylvania in Philadelphia, and colleagues.

http://abcnews.go.com/Health/Cholesterol/wide-variations-found-red-yeast-rice-supplements/story?id=11966172



TESTS OF TEN RED YEAST RICE SUPPLEMENTS BY CONSUMERLAB.COM REVEAL SIGNIFICANT STATIN LEVELS, BUT SOME PILLS CONTAMINATED

Popular Cholesterol-Lowering Supplements Compared in New Report

WHITE PLAINS, NEW YORK — JULY 1, 2008ConsumerLab.com announced today that its tests of ten red yeast rice supplements revealed levels of cholesterol-lowering statin compounds varying by more than 100-fold, with some supplements providing as much as prescription medication and others containing very little. A potentially toxic contaminant, citrinin, was found in four of the products, with highest levels in a supplement sold by a national pharmacy chain.

Red yeast rice naturally contains the cholesterol-lowering statin compound lovastatin, the active ingredient in prescription Mevacor. Labels on red yeast rice products, however, generally do not disclose their lovastatin content due to concern that the supplement will be considered a drug by the FDA and removed from the market. This makes it difficult for consumers and doctors to assess and compare red yeast rice supplements, although they remain widely used.

http://www.consumerlab.com/news/Red_Yeast_Rice_Supplements_Tests_Comparison_Lovastatin/7_1_2008/



Red Yeast Rice May Lower Cholesterol



Study Shows Supplement Reduces LDL Cholesterol Levels

By Salynn Boyles

WebMD Health News

Reviewed by Louise Chang, MD



calcium_no_weight_loss.jpg

June 17, 2009 -- By some estimates, as many as 10% of people who take cholesterol-lowering statins experience troubling muscle pain, and many stop taking the drugs because of it.

Now a new study suggests that a dietary supplement sold in nutrition centers and grocery stores may be a useful alternative to statins for some.

http://www.webmd.com/cholesterol-management/news/20090617/red-yeast-rice-may-lower-cholesterol



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Friday 24 June 2011

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Super Omega-3 fat protects the heart and arteries and can prevent blindness

Salmon Trout Super Omega 3 fat protects the heart and arteries and can prevent blindness
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(NaturalNews) As the population of American baby boomers continues to swell, age related afflictions including diabetes, cardiovascular disease and complications such as blindness are growing at a similar pace.

Wednesday 15 June 2011

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Tuesday 14 June 2011

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Sunday 12 June 2011

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What is Resveratrol?
Resveratrol or trans-resveratrol as it is sometimes called a phytoalexin which is naturally produced by a variety of plants when under attack by pathogens like bacteria or fungi. Resveratrol is also produced through chemical synthesis from Japanese knotweed. Resveratrol has also been discovered in the skin of red grapes and is also a constituent of red wine
What does resveratrol do?

Resveratrol may help prevent diseases and other age-related deterioration. In studies performed on lab mice, researchers have found that resveratrol may have several positive health effects including: Preventing heart disease Preventing Type 2 diabetes preventing certain types of cancer, including prostate and breast cancer Preventing Alzheimer's Increasing bone health counteracting a high-fat diet aiding in weight loss Increasing life span

Red wine was believed to be associated with heart health and connected to the healthier diets of Mediterranean peoples. This included the French who like Americans, consume fattier foods but have less heart disease. Resveratrol is the link to the benefits of drinking red wine.

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Vitamin B12 also called cobalamin, is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis and energy production. As the largest and most structurally complicated vitamin, it can be produced industrially only through bacterial fermentation-synthesis.

Vitamin B12 consists of a class of chemically-related compounds (vitamers), all of which have vitamin activity. It contains the biochemically rare element cobalt. Biosynthesis of the basic structure of the vitamin in nature is only accomplished by simple organisms such as some bacteria and algae, but conversion between different forms of the vitamin can be accomplished in the human body.

A common synthetic form of the vitamin, cyanocobalamin, does not occur in nature, but is used in many pharmaceuticals and supplements, and as a food additive, due to its stability and lower cost. In the body it is converted to the physiological forms, methylcobalamin and adenosylcobalamin, leaving behind the cyanide, albeit in minimal concentration. More recently, hydroxocobalamin (a form produced by bacteria), methylcobalamin, and adenosylcobalamin can also be found in more expensive pharmacological products and food supplements. The utility of these is presently debated.

Historically, vitamin B12 was discovered from its relationship to the disease pernicious anemia, which is an autoimmune disease that destroys parietal cells in the stomach that secrete intrinsic factor. Intrinsic factor is crucial for the normal absorption of B12, so a lack of intrinsic factor, as seen in pernicious anemia, causes a vitamin B12 deficiency. Many other subtler kinds of vitamin B12 deficiency and their biochemical effects have since been elucidated.

Wednesday 1 June 2011

Resveratrol Protects Brain After A Stroke

Resveratrol Protects Brain After A Stroke

Scientists from John Hopkins University recently published their findings in a study on lab mice that showed resveratrol may shield the brain from the negative affects of a stroke. The researchers, lead by Dr Sylvain Dore, state that it may not be resveratrol that is inhibiting the brain damage directly, but it may actually be activating the cells to defend themselves from the free radical damage that often follows a stroke

Thursday 26 May 2011

Red wine compound increases anti-tumor effect of rapamycin

http://www.sciencedaily.com/releases/2011/02/110214142335.htm

ScienceDaily (2011-02-14) -- Researchers have discovered that resveratrol -- a compound found in red wine -- when combined with rapamycin can have a tumor-suppressing effect on breast cancer cells that are resistant to rapamycin alone. The research also indicates that the PTEN tumor-suppressing gene contributes to resveratrol's anti-tumor effects in this treatment combination.